Introduction: Pharmaceutics and drug delivery

Introduction to Polymeric Drug Delivery

Materials for Pharmaceutical Dosage Forms: Molecular Pharmaceutics and Controlled Release Drug Delivery Aspects

Controlled release delivery is available for many routes of administration and offers many advantages (as microparticles and nanoparticles) over immediate release delivery. These advantages include reduced dosing frequency, better therapeutic control, fewer side effects, and, consequently, these dosage forms are well accepted by patients. Advances in polymer material science, particle engineeri...

Pharmaceutics, Preformulation and Drug Delivery Conformational Polymorphism on Imatinib Mesylate: Grinding Effects

Crystal structures of polymorphs " and $ of imatinib mesylate were obtained. Thermal behavior and grinding effects were studied by X-ray powder diffraction and differential scanning calorimetry techniques. Molecules in forms " and $ exhibit significant conformational differences due to dissimilar intramolecular interactions, which stabilize their molecular conformations. In spite of that, both ...

An Introduction to Drug Delivery for Chemical Engineers

• Multidisciplinary education through collaborative laboratory and course work • Teamwork as the necessary framework for solving complex problems • Incorporation of state-of-the-art technologies throughout the curricula • Creation of continuous opportunities for technical communication. The Rowan program emphasizes these essential features in an eight-semester, multidisciplinary, engineering cl...

Pharmaceutical characterization of novel tenofovir liposomal formulations for enhanced oral drug delivery: in vitro pharmaceutics and Caco-2 permeability investigations

Tenofovir, currently marketed as the prodrug tenofovir disoproxil fumarate, is used clinically to treat patients with HIV/AIDS. The oral bioavailability of tenofovir is relatively low, limiting its clinical effectiveness. Encapsulation of tenofovir within modified long-circulating liposomes would deliver this hydrophilic anti-HIV drug to the reticuloendothelial system for better therapeutic eff...